SAFETY
CBD safety and side effects: what is known
Is CBD safe, and what are the side effects?
In short
Major reviews describe CBD as generally well tolerated in humans. Side effects, when they occur, tend to be mild, and the most important practical issue is potential interaction with other medicines.
What studies have observed
- The WHO review concluded CBD has a good safety profile and is not associated with abuse or dependence.
- Reported side effects can include tiredness, changes in appetite, or digestive upset.
- CBD can affect how the body processes certain medications via liver enzymes.
Read this with caution
- Long-term safety data, especially at high doses, is still limited.
- Product quality varies, testing and a COA matter for what is actually in the bottle.
- This is general information, not medical advice.
The bottom line
CBD is generally well tolerated, but if you take medication, are pregnant or breastfeeding, talk to a healthcare professional first, and choose lab-tested products.
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Related terms
References
Last reviewed 2026-06-01. Educational content only, not medical advice. CBD products are food supplements and are not intended to diagnose, treat, cure or prevent any disease.